abstract：:In contradistinction to the increased fraction of HeLa S 3 cells in S phase after irradiation by a single dose in a range of 25--200 R, cultures irradiated by a second dose at time of morphologic restitution of mitotic activity exhibited decreased fraction of cells in S phase. The interpretation is that passage from G...

journal_title：Neoplasma

authors： Siracká E

更新日期：1976-01-01 00:00:00

abstract：:Mode of releasing of associated 4S RNA species was studied during a controlled transition of aggregate structure of high-molecular-weight AMV-RNA. It has been found that associated 4S RNA constitutes 2.5% of 60S AMV-RNA complex. Approximately 60% of associated 4S RNA is successively released during treatment of viral ...

journal_title：Neoplasma

authors： Trávnícek M,Ríman J

更新日期：1976-01-01 00:00:00

abstract：:Up to 19--20 fractions of separate RNA species and groups have been revealed in malignant tumors of the stomach and mucous membrane of patients with stomach cancer, ulcer and polyposis of the stomach by means of the method of analytical and preparative electrophoresis in 2.5% polyacrylamide gel. A more intensive incor...

journal_title：Neoplasma

authors： Seitz JF,Kalinvosky VP

更新日期：1976-01-01 00:00:00

abstract：:The levels of nicotinamide adenine dinucleotide (NAD) and NADH in blood of patients with cancer in various stages of development as well as their modification after glucose administration were determined in 188 respectively 77 cases. NAD was significantly decreased in patients with cervix and breast carcinoma but unal...

journal_title：Neoplasma

authors： Comes R,Mustea I

更新日期：1976-01-01 00:00:00

abstract：:During the course of 16 years, i. e. from 1953 to 1968 inclusively, a total of 2111 patients with carcinoma of the uterine cervix were treated at the Oncological Institute in Brno. Of these, 1829 patients, i. e. 86.6% were irradiated, 282, i. e. 13.4% underwent primarily a radical excision and subsequently were irradi...

journal_title：Neoplasma

authors： Ptácková B

更新日期：1976-01-01 00:00:00

abstract：:5-Azacytidine administered to male mice prior to mating resulted in their decreased fertility and in the loss of offsprings at different periods of embryonic and postnatal development. The drug interfered with mature spermatozoa and spermatids; considerable distortion of cellular associations in seminiferous epitheliu...

journal_title：Neoplasma

authors： Seifertová M,Veselý J,Cihák A

更新日期：1976-01-01 00:00:00

abstract：:Analysis of literary data and the author's findings have shown that the transplacental action of most of the compounds tested in experiments on rats manifested itself by a neurotropic carcinogenic effect. A marked neurotropism in transplacental carcinogenesis in rats is characteristic even for such drugs (e.g. dimethy...

journal_title：Neoplasma

authors： Alexandrov VA

更新日期：1976-01-01 00:00:00

abstract：:A modification of the "skin window" method is proposed for investigation of delayed hypersensitivity in patients with tumors. The principle of the modified method consists in an antigen injection into the site of lesion. Patients with tumors showed a strikingly lowered lymphoid cells and eosinophilic and basophilic gr...

journal_title：Neoplasma

authors： Jansa P,Jorda V,Sternberský J

更新日期：1976-01-01 00:00:00

abstract：:In contrast to the B77 virus, its B77(RBI) rat variant continuously produced by the rat RBI sarcoma cells in vivo and in vitro, efficiently induced progressively growing tumors in hamsters and transformed hamster embryo cells in vitro. Both, induced tumors and transformed cell cultures showed production of infectious ...

journal_title：Neoplasma

authors： Svec J,Hilubinová K,Lizorová V,Thurzo V

更新日期：1975-01-01 00:00:00

abstract：:Inhibiting activity of blood serum was determined from the decrease of N-acetyl-hexosamine end groups of hyaluronic acid products released by testicular hyaluronidase. Maximum inhibition was observed within the region of pH from 6.5 to 6.8. Correlation between the serum concentration and its inhibiting effect on hyalu...

journal_title：Neoplasma

authors： Kolárová M

更新日期：1975-01-01 00:00:00

abstract：:On the basis of the author's own results and literary data emphasis is laid on the significance of lymphography for confirming or establishing a diagnosis, for determining the extent of a lesion and for proper considerations on indications for surgical treatment. Relymphography following a surgical intervention is cap...

journal_title：Neoplasma

authors： Kutarna A

更新日期：1975-01-01 00:00:00

abstract：:Mouse lymphosarcoma LS/BL cells growing in tissue culture were irradiated with 100, 316 and 1000 R respectively and fixed 5, 15 or 60 minutes later. Semithin sections were studied under a light and ultrathin under an electron microscopes. Under the light microscope, differences between the morphology of individual nuc...

journal_title：Neoplasma

authors： Tkadlecek L,Karpfel Z,Cibulka M,Viklická S,Spurná V

更新日期：1975-01-01 00:00:00

abstract：:The cytostatic activity of 2-thio-4-hydrazinouracil (THU) on some transplantable tumors has been studied. A strong effect of this compound (between 60% and 100% suppression) has been found in the case of Myeloma P-8 (MOPC-21) and Sarcoma 180 (Crocker). A less pronounced effect has been observed on Yoshida sarcoma, whi...

journal_title：Neoplasma

authors： Golovinsky EV,Emanuilov EA,Spassovska NC,Spassov AV

更新日期：1975-01-01 00:00:00

abstract：:Transplacental effect of benzo(a)pyrene was studied in organ cultures of embryonic lung tissue explanted from mouse donors injected by the carcinogen. Hyperplastic alteration of epithelium, followed by adenomatous changes were seen in embryonic lung tissue cultures from donor mice injected by benzo(a)pyrene. No altera...

journal_title：Neoplasma

authors： Shabad LM,Kolesnichenko TS,Nikonova TV

更新日期：1975-01-01 00:00:00

abstract：:Active human serum manifests a tumoricide effect against cells of the Ehrlich ascites tumor. Sera of patients with Ca ventriculi show a higher effect than those of patients with a chronic streptococcal disorder, in comparison with intact subjects. This tumorcide effect is depressed by Varidase, the degree of depressio...

journal_title：Neoplasma

authors： Mikolásek J

更新日期：1975-01-01 00:00:00

abstract：:Some selected data on cancer statistics in the USSR and results of the nationwide cancer screening activities are presented. The usefullness of some new methods in prophylactic examination is discussed. ...

journal_title：Neoplasma

authors： Alexandrov NN

更新日期：1975-01-01 00:00:00

abstract：:The paper deals with some results of work done in the USSR to establish maximal allowable doses (MAC) for the carcinogenic hydrocarbon benza(a)pyrene in human environment. At the same time it is a brief review of some discussions on this item which took place in USSR and on the international level. ...

journal_title：Neoplasma

authors： Shabad LM

更新日期：1975-01-01 00:00:00

abstract：:It has been shown by a number of authors that the antibiotic chloramphenicol (CP), produced in the USSE under the name of levomycetin, had considerably inhibited the growth of liver tumors, induced by various carcinogenic compounds [3,7,8,21]. Moreover, it has been found by ourselves and other authors that CP greatly ...

journal_title：Neoplasma

authors： Shabad LM,Bogush TA,Belitsky GA

更新日期：1975-01-01 00:00:00